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J Pharmacol Sci

Overall, the most chemically reactive group of GSH is the thiol (SH) group in cysteine

Signs of Insulin Resistance: Skin tags, dark patches (acanthosis) Sugar cravings Fatigue after meals Midsection weight gain Testing: Fasting glucose, insulin HOMA-IR calculation Hemoglobin A1c Treatment Strategies: Low glycemic diet (limit sugar, dairy, refined carbs) Time-restricted eating or fasting Exercise (especially resistance training) Support with: Chromium, inositol Peptide options : CJC-1295 + Ipamorelin, Tesamorelin, and MOTS-c support metabolic health and insulin sensitivity

doi: 10.1210/endo.139.10.6216 37 BulayevaNNWatsonCS

Proper dosing and monitoring are important due to its copper-binding properties