In general, it should be noted that the toxin-based models replicate nigrostriatal dopaminergic cell loss and neuroinflammation, but lack progressive characteristic and overt -synuclein pathology [218]
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Rus GZ, Bernardini A, dos Santos M, Mendes Abelaira H, Luis Maciel A, Orlandi Arent C, Iladi Matias B, Bruchchen L, Maria Igncio Z, Michels M, Dal-Pizzol F (2016) Antioxidant therapy alters brain MAPK-JNK and BDNF signaling path-ways in experimental diabetes mellitus
Hyperoxygenation ameliorates stress-induced neuronal and behavioral deficits
Sigma), DMSO (Sigma), IKE (0.25M