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What Is a Herxheimer Reaction

J Cancer 8(17):34163429 Podgrska-Kryszczuk I (2024) Spirulina-an invaluable source of macro- and micronutrients with broad biological activity and application potential

Abbreviations CQ: Chloroquine CSCs: Cancer stem cells ER: Estrogen receptor-alpha GPxs: Glutathione peroxidases GSH: Glutathione HCC: Hepatocellular carcinoma hiPSC-MSCs: Mesenchymal stem cells drived from human induced pluripotent stem cells IBC: Inflammatory breast cancer IH: Isorhamnetin LOH: Loss of heterozygosity MnSOD: Manganese superoxide dismutase NAC: N -acetylcysteine PHGPx: Phospholipid GPx ROS: Reactive oxygen species TNBC: Triple-negative breast cancer TFAP2C: Transcription factor AP-2 gamma References Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A

Experiments were performed in accordance with the Guidelines by the NIH Office of Laboratory Animal Welfare regarding the care and use of animals for experimental procedures, and following the recommendations stated in the ARRIVE guidelines ( The experiments were approved by the UTHealth-Houston Animal Welfare Committee (AWC) under animal protocol number 21-0065