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Beyond lung cancers, epidemiological associations and biological plausibility link cigarette smoking to increased risk of cancers all along the aerodigestive tract including oral, pharyngeal, laryngeal, Breast, esophageal, stomach, pancreatic, bladder, cervical, kidney, and colorectal cancers

When Nicotine is inhaled it goes into the lungs, where it gets transported by your bloodstream, enters the kidneys then the heart and ends up in the brain, which results in a tolerance to nicotine

Alterations in vascular function associated with the use of combustible and electronic cigarettes

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