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In our study, we explored the innate function of SP toward SMs and osteoclasts, and offered a targeted therapy of RA by a macrophage-cell-membrane-cloaked Spirulina platensis (denoted as SP@M) (Fig

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After washing in PBS, primary antibodies (IgM-PE BioLegend 406507, IgD-APC BioLegend 405713, MARCO Santa Cruz sc-65353/ anti-rat PE Abcam ab97058 and Siglec-1 Biolegend 142417) diluted in PBS 10% FCS were incubated overnight at 4 C

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