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GHK-Cu produced a concentration-dependent increase in the accumulation of connective tissue, measured as higher collagen and glycosaminoglycan content, higher DNA and protein, and increased collagen mRNAs in the harvested granulation tissue, while an inactive control peptide did not

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*Correspondence: Aalt Bast, Department of Toxicology, Faculty of Health, Medicine and Life Sciences, Maastricht University, P

doi: 10.1210/jc.2017-01922 19 WangYFGuPZhangJQiRde VeerMZhengGet al

doi: 10.1016/S0022-3476(05)80970-9 38 ThorntonPSAlterCAKatzLEBakerLStanleyCA