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Effect of JNJ-42165279 on anandamide levels Plasma concentrations of JNJ-42165279 correlated strongly with AEA levels at the corresponding time point (r s [133] = 0.67, p 5% of participants in any treatment arm are reported in Supplementary Table S7 (for all AEs see Supplementary Tables S8)

[63] have assessed the effect of zinc deficiency and zinc supplementation on antioxidant expression in high-fat diet mice, inducing vascular inflammation and oxidative stress, demonstrating that zinc insufficiency exacerbates antioxidant expression, whereas zinc supplementation improves that expression