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This is another reason why higher concentrations (10-20mg/mL) are preferred for higher doses, and why the reconstitution charts emphasize these concentrations for the escalation and maintenance phases

High-intensity cardio is less important during this combination

These effects may help some patients eat less and manage their progress more effectively under medical supervision

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Use caution in patients with a history of anaphylaxis or angioedema to other GLP-1 receptor agonists because it is unknown whether such patients will be predisposed to serious reactions with semaglutide