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At the same time, bile acid signaling pathways, including the farnesoid X receptor (FXR)FGF15 and TGR5glucagon-like peptide-1(GLP-1) axes, are disrupted, further promoting hepatic lipid accumulation and immune dysregulation

Malnutrition, particularly cachexia, is commonly observed among cancer patients and can lead to adverse treatment outcomes and reduced quality of life

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These links were expected to support better SBIR topic development and to encourage the creation of lists of SBIR awards in alignment with highest priority Product Center needs