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Cancer-cell metabolism studies NNMT is overexpressed in several cancer cell lines, and 5-Amino-1MQ has been used in vitro to characterise its role in tumour metabolism

[1] For example, if a 2 mL dose (full 200 mg thiamine, 200 mg niacinamide) is to be given IV, a nurse might mix it into 50 mL of saline and infuse over 15-30 minutes