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Suitability for Different Skin Types Hydroquinone may be appropriate for: Severe melasma under dermatological care Short-term corrective treatment Patients who can strictly follow usage limits Alpha arbutin is better suited for: Mild to moderate pigmentation Acne marks and sun spots Sensitive or reactive skin Long-term brightening routines Beginners in pigmentation treatment For most people, alpha arbutin offers a safer entry point into skin brightening

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Depending on the subjects recovery, researchers may continue to administer a lowered maintenance dosage of 1mg daily until full or near-full recovery

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Especially, Fennel seed containing mainly anethole, a phytoestrogen volatile oil, possesses antioxidant and antimicrobial activities [86]