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Dose-dependent FAK and paxillin phosphorylation in rat tendon fibroblasts, promoting cell migration and ECM remodeling without direct effect on basal proliferation

doi: 10.1038/s41577-024-01112-7 136 PhanATGoldrathAWGlassCK

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In a 2017 study published in the Journal of Molecular Medicine , Hsieh and colleagues reported that BPC-157 promoted angiogenesis in chick chorioallantoic membrane and endothelial tube-formation assays and accelerated blood-flow recovery in a rat hindlimb ischemia model, with the effect attributed to activation of the VEGFR2-Akt-eNOS signaling pathway [1]

Association of bile duct and gallbladder diseases with the use of incretin-based drugs in patients with type 2 diabetes mellitus