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The chronic state of neuroinflammation thus creates an environment that is detrimental to synaptic function and plasticity, contributing to the cognitive and emotional deficits observed in individuals with chronic alcohol use

10.3389/fimmu.2015.00223 105 De VriesY

doi: 10.1016/j.biopsych.2005.04.043

Creatinine is a breakdown product of phosphocreatine from muscle (Baynes 2014)

Persistent nausea, vomiting, or abdominal pain Chest tightness or difficulty in breathing Dizziness and fainting Increased heartbeat Fatigue Worsening of existing medical conditions Severe skin rashes If you have any of these symptoms that do not seem mild or normal, you should immediately turn to a professional healthcare provider