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Icariin alleviates ferroptosis-related atherosclerosis by promoting autophagy in xo-LDL-induced vascular endothelial cell injury and atherosclerotic mice

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It improves glucose metabolism in skeletal muscle, which implies a number of benefits for those with diabetes, obesity, or who are over 30 years old

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However, it was reported that MTX could cause intestinal damage via producing reactive oxygen species (ROS) and transcription factor activation as NF-B (Miyazono et al