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Bio-psycho-social treatment should be proposed in that order

Such cessation targeting is essential as fewer older adults express interest in quitting or making a quit attempt compared with younger adults [37], highlighting the critical need for effective interventions, given that only 5% of older adults successfully quit smoking annually [38]

For pipe tobacco, we found that the risk of hypertension increased rapidly and then decreased with growing average daily consumption without adjustment, and with the adjustment only for sex and age

Conclusion Although all the mechanisms mentioned above help explain the impact of cigarette smoke on CD and UC, they fail to explain the opposite effects on intestinal inflammation

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