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Given that homocysteine levels increase in Plasmodium infected erythrocytes, we asked if high homocysteine could play a role in inducing gametocytogenesis

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The upregulation of Trx1, however, did not seem to compensate fully for the loss of TRP14 activities, because when assessing cystine reduction using BODIPY-labeled cystine, which becomes fluorescent upon reduction of its disulfide (Pader et al, 2014), TRP14 deletion severely hampered the strong fluorescence seen in control cells (Fig

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doi: 10.1080/10408398.2024.2416481 64 MiquelS.MartnR.RossiO.Bermdez-HumarnL