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The two anti-insulin antibodies were mixed in a 1:2 donor (cryptate)/acceptor (XL665) ratio in the insulin assay detection buffer (Cisbio Bioassays) and 15 L of the insulin antibody mix was added per well

It is FDA-approved for reducing visceral fat in individuals with HIV-associated lipodystrophy and has also been studied for metabolic health, fat loss, and aging-related applications

When constrained by concurrent incretin receptor activation, glucagon receptor agonism may serve as a complementary catabolic signal that amplifies weight loss and metabolic improvement

doi: 10.1002/advs.202411479 29 JialiHXiankangZHuiZYuLHuidanHZhiyuLet al

Surrogates are not outcomes