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SKU: 10660346204

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Cell (2014) 157:132438

doi: 10.1093/ehjcvp/pvad080

Sulfonylurea drugs affect sulfonylurea receptor 1 (SUR 1), which leads to the closure of adenosine triphosphate (ATP)-dependent potassium channels, preventing potassium from leaving the cell and depolarizing the cell membrane, leading to an influx of calcium and triggering insulin release