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doi: 10.1212/01.wnl.0000225050.57553.6d

These methodological gaps substantially limit the interpretation, reproducibility, and translational potential of the current findings

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On the other hand, the current results disagree with the study of Manggabarani and colleagues , who observed statistically significant skin brightness in patients who used a combination of topical glutathione 2%, tocopheryl acetate 1%, and 3% magnesium ascorbyl phosphate