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10.3390/ijms21217977 [DOI] [PMC free article] [PubMed] [Google Scholar] Scarpino S., Di Napoli A., Taraboletti G., Cancrini A., Ruco L
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The compound demonstrates exceptional target selectivity, with no inhibition of related methyltransferases (DNMT1, PRMT3, COMT) or NAD+ salvage enzymes (NAMPT, SIRT1) at concentrations up to 600 M
Common problems include inconsistent dosing, label discrepancies, and endotoxin contaminants like lipopolysaccharides, which can provoke systemic inflammation
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