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In addition to its role in histone acetylation the ACSS2 encoded enzyme also functions as a lactoyl-CoA synthetase

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2018;61:M1M12

For a 10 mg lyophilized vial: At 2.5 mg/week: 4 weeks of doses (perfectly matches the 28-day stability window) At 5 mg/week: 2 weeks of doses (well within stability limits) For a 30 mg lyophilized vial: At 2.5 mg/week: 12 weeks of doses (far exceeds 28-day window, significant waste) At 5 mg/week: 6 weeks (exceeds window by 2 weeks) At 7.5 mg/week: 4 weeks (perfect alignment) At 10 mg/week: 3 weeks (fully within stability limits) The reconstitution volume you choose affects how easy it is to measure each dose but does not change these timelines