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et al., 2022) highlight PDs significant renoprotective impact against ferroptosis in Cis-induced AKI models, achieved through multiple mechanisms: limiting excessive cellular iron accumulation, decreasing ROS generation, preserving GSH levels, boosting GPX4 functionality, thus minimizing lipid oxidation and ferroptotic susceptibility, ultimately decelerating AKI progression

VSMCs were cultured in 12-well plates for 48 h

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Patients with dementia have a reduction in glutathione and its ability to be recycled (8)