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doi: 10.1016/j.bioactmat.2023.10.002

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Excessive Fe 2+ impairs the function of pancreatic cells and liver cells through oxidative stress and mitochondrial injury, leading to insulin resistance and affecting NAFLD development ( 2+ , elevates ROS levels, and leads to ferroptosis ( in vitro and in vivo ( Intervention effects of herbs or herbal extracts in regulating ferroptosis on non-alcoholic fatty liver disease Currently, there is no agreed standard or definitive effective drugs for the treatment of NAFLD