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Wittstock, U., Kliebenstein, D

Back in Australia, Bridge and Zarka continue with their work to use new techniques and state-of-the-art engineering, to optimize the technology so that production can be scaled up even more

Of note, the commercial Iscoves Modified Dulbeccos Medium (IMDM) and Serum Free Expansion Medium (SFEM), which were used as the basal medium for erythroblast cultures, contain a supraphysiological concentration of cystine at 292 M as compared to physiological plasma concentration of 4075 M cysteine in SCD patients, which decreased further to 3060 M during vaso-occlusive pain episodes 36

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Biochem Biophys Res Commun