Specifically the central actin-sequestering domain of this 43-amino acid endogenous peptide
doi: 10.3390/ijms22179274 41 LiangYWuJWangWXieHYaoS
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Based on the evidence emerging from the recent trials showing that NAC can reduce exacerbations in patients with COPD, including those taking ICS, the 2020 Global Initiative for Chronic Obstructive Lung Disease (GOLD) report includes NAC, as well as other thiol-based drugs, as additional therapies to consider in the treatment of COPD [33]