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In the hapten model, the photoproduct binds to protein within the cutaneous tissue (haptenization) to form a complete antigen [57, 86]

PTMs are critical molecular events in a series of biological processes such as cell growth, proliferation, differentiation, metabolism, and apoptosis ( Protein oxidation Cysteine residues in proteins are easily oxidized by ROS, reactive nitrogen species, reactive sulfur species, or GSH

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It adheres to epithelial cells via fibronectin-binding proteins (FnBPs) and evades host immunity through biofilm formation and intracellular persistence