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BPC-157 is an exception because it is not an exogenous peptide being introduced into a foreign environment: it is a peptide found naturally in human gastric juice at low concentrations, where it appears to serve a mucosal protective function

The sole human study identified by the 2025 systematic review was a retrospective case series of 12 patients who received intra-articular BPC-157 injections for knee pain

It is a semisolid preparation designed for convenient and controlled application on the skin for localized treatment or absorption of active ingredients

For treating glaucoma and other eye conditions, animal studies show that the BPC-157 normalizes optic nerve pressure and enhances ocular blood flow