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doi: 10.1056/NEJM199107043250103

Alpha-Blockers (Examples: Tamsulosin, Alfuzosin, Silodosin ) Action: Relax muscles around the bladder neck and prostate Onset: Quickoften within days Efficacy: Improves symptoms in 6070% of men Limitations: Does not shrink prostate or prevent progression Side Effects: Dizziness, blood pressure decrease Retrograde ejaculation Nasal congestion Risk of floppy iris syndrome in eye surgery 2

Raw fluorescence values were corrected for background fluorescence, which was measured in wells without cells containing only medium, one-step assay buffer and test compound

Methods 61 , 156164 (2013)

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