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70 In breast cancer, hypermethylation of the CDO1 promoter, which is frequently observed, is a predictor of poor outcome in anthracycline-treated, oestrogen receptor-positive and lymph-node-positive patients

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Well-designed randomized clinical studies are needed to systematically evaluate the evidence for the use of these hepatoprotective agents as treatment options for APAP-induced liver injury, to determine the timing of initiation of the therapy, and to further define the optimal treatment regimen

Intriguingly, when the hydraulic resistance is infinite, nearly all cells move towards the lower hydraulic resistance geometries [200]