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Extracellular vesicles and immune response during pregnancy: a balancing act

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Another major driving hypothesis states that these conditions, by increasing reactive oxygen species (ROS) and nitrogen species (RONS), are capable of altering the balance of the redox status of both the steroidogenic cell population and the germ line cell populations, causing the disruption of the hypothalamicpituitarytesticular axis and the impairment of sperm quality [22]