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The trial product estimand addressed the average treatment effect in all randomly assigned participants, assuming that the drug or placebo was taken as intended (participants on treatment)

Phys Occup Ther Pediatr 2017;37:292307

Some clients require ongoing B12 supplementation due to conditions such as pernicious anemia, certain gastrointestinal disorders, or a history of surgeries that affect absorption

Quite often we actually know little about the daily recommended dosage, accurate absorption rates, quality and even which vitamins and minerals are better for us as individuals

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