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Expanding the psoriasis disease profile: interrogation of the skin and serum of patients with moderate-to-severe psoriasis

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205 Loss of key autophagy genes, such as BECN1 and ATG5, predisposes mice to diverse cancers, including lung adenocarcinoma, B-cell lymphoma, and hepatocellular carcinoma, 206,207 highlighting the essential role of autophagy in maintaining cellular integrity

For example, proteins such as histone 1, H2A, H4, and leucine-rich repeat protein are overexpressed in antimony-resistant parasites, while proteins like the kinetoplastid membrane protein (KMP-11) are under-expressed (Kazemi-Rad et al., 2013)

Recent studies have shown that POP patients have significantly higher levels of TGF-1 and MMP-3 mRNA expression than non-POP patients do, indicating the severity of POP (Chen et al