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[2] Risk factors may occur possibly more in elderly people due to impaired intestinal absorption, and in children, premenopausal women, and pregnant women, whose diets are low in animal foods

Requires minimal time

[6/7] malignancy Parenchymal brain tumor (either primary or metastatic)

Timing & Dosage Considerations Split Dosing: Many protocols divide the daily dose into two or three smaller administrations to maintain steady blood levels