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Antioxidants like glutathione and vitamin C help reduce dark spots, even skin tone, and combat dullness for a more luminous complexion

10.1136/thx.48.10.959 [DOI] [PMC free article] [PubMed] [Google Scholar] Gruchlik A., Chodurek E., Dzierzewicz Z

TAMs are responsible for the release of epidermal growth factor (EGF) in OC, which directly activates the EGF receptor (R)-ERK pathway (101)

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Although depletion of CD8 PD-1+ T cells leads to a decrease in their cytotoxic capacity and impaired control of chronic infections or tumors, this phenotype is thought to be adapted to minimize tissue damage while maintaining a critical level of pathogen control (223, 301, 303)