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456 In the spinal cord, the influx of neuropathic signals to the dorsal horn leads to central sensitization, characterized by increased spontaneous neuronal activity, lowered activation thresholds for peripheral stimuli, heightened responses to sub-threshold stimuli, and expansion of receptive fields

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Primary Cellular Pathways BPC-157: FAK/Paxillin Signaling Cell Migration & Adhesion Research has demonstrated that BPC-157 significantly increases phosphorylation of focal adhesion kinase (FAK) and paxillin proteins in fibroblast cells[1]

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