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24 days) selectively inhibits growth and induces necrosis in PHGDH-dependent MDA-MB-468 orthotopic breast cancer xenografts in NOD.CB17-Prkdc scid /J mice without causing weight loss [2]

Patient Demographics Patient pain scores before and after the treatment were compared using a paired t test to evaluate statistical significance

Interestingly, the VEGF expression profile in TAM correlated with the one of MMP-9, a matrix metallopeptidase contributing to the degradation of the ECM and facilitating endothelial cell migration (58)

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