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Nasal spray offers an alternative that eliminates these concerns while introducing its own set of considerations

It has been studied for tissue repair and inflammation in many animal models

Cautions : DO NOT TAKE large doses of vitamins (megadoses or megavitamin therapy) unless directed to by your doctor

Gastrointestinal effects: the main titration bottleneck Nausea, diarrhea, constipation, and vomiting run around 40 to 44% overall, dose-dependent in how many people report them but mild-dominant in severity: severe events stay at or below about 1.7% in any category even at the top dose. In the obesity program the by-dose rates run nausea 25/29/28%, diarrhea 19/21/23%, and vomiting 8/11/13% at 5/10/15 mg. They concentrate during escalation and ease with time on a held dose

That makes it a promising option for many patients who have sufferedsometimes for years with chronic pain