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Using the same spot repeatedly leads to lipohypertrophy, hardened fatty deposits that impair absorption

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Since anxiety impairs cognitive function, this dual action produces greater net cognitive improvement than pure nootropics in anxious individuals

For instance, a patient with borderline low B-vitamin levels might receive 0.5 mL IM weekly, whereas someone with severe malabsorption could receive 1-2 mL IM two to three times per week initially

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