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Cachexia is a more advanced form of wasting that happens in people with serious chronic illnesses like cancer, heart failure, kidney failure, COPD, or HIV

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We merged genes from the three databases to create a gene set for each pathway (Additional file 1: Tables S2S4), resulting in 5325, 2557, and 3435 genes for Most Studied Pathways, Gene-Associated Pathways, and Popular Pathways, respectively

AOD-9604 targets fat metabolism, MOTS-c activates cellular energy pathways, Tesamorelin reduces visceral fat, and Ipamorelin supports lean muscle a four-pronged approach to body recomposition

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