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(2020) 223:921.e1921.e10

This evidence supports a multi target therapeutic paradigm that is consistent with the multifactorial nature of ASD and suggests that combined interventions, for example, omega3 with vitamin D or vitamin E, or cysteine rich proteins to boost glutathione, may exert additive or synergistic effects across redox, mitochondrial, and immune pathways (Castejon et al., 2021