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Histologically, the condition is characterized by the presence of regenerated nodules encased in dense fibrous septa, leading to the disappearance of parenchyma and subsequent collapse of liver structure (Schuppan and Afdhal, 2008

PLA2G2F from both isoform constructs showed the strongest colocalization with the ER marker PDI, indicating ER localization

References: Baccarelli A, et al