468 Specifically, these agents can attenuate the excitability of carotid body cells and diminish sympathetic activation, ultimately leading to a reduction in sympathetic responses
Nevertheless, MOTS-c has been used less frequently in disease treatment, and no effective method of applying MOTS-c in the clinic has been developed
Many who use it for joint recovery report a decrease in pain, which can significantly improve quality of life for those with limited mobility
However, TCAs are generally recommended as second-line treatments due to their higher risk of adverse effects, including orthostatic hypotension, dry mouth, constipation, urinary retention, memory impairment, hallucinations, and confusion [157]
Nasal delivery systems are gaining share for their bioavailability and convenience