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Our body naturally makes small amounts of them during normal chemical processes

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Precision in therapeutic approaches targeting CAFs is crucial, as strategies focusing on CAF depletion may inadvertently lead to loss of other tumour-suppressive cells, potentially exacerbating tumour aggressiveness

Therefore, it may be hypothesized that HCV produces oxidative stress through multiple mechanisms that include chronic inflammation, iron overload, and liver injury [103]

Growing evidence suggests FMT holds promise for treating various CLDs, including MASLD, PSC, chronic hepatitis B, and HCC 171,172,173,174