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Common causes include metabolic diseases as diabetes, autoimmune diseases, vitamin deficiencies, infections, and chemotherapy, often leading to a glove and stocking sensation changes

2 Molecular mechanisms of ferroptosis Ferroptosis, a novel form of cell death distinct from apoptosis, pyroptosis and autophagy, is an iron-dependent programmed form of cell death characterized by an iron metabolism disorder, imbalance of the redox system and the accumulation of lipid peroxides (6, 7)

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