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PURINE CATABOLISM In addition to GSH redox coupling mechanism and NO signaling, purine catabolism ( Figure 2 ) may be a previously unappreciated component of the homeostatic response of mitochondria to oxidant stress and may play a critical role in slowing progressive mitochondrial dysfunction in certain disease states (Kristal et al., 1999)

Consensus for tinnitus patient assessment and treatment outcome measurement: tinnitus research initiative meeting, Regensburg, July 2006

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