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Callaghan, 2014

Several nutrients and food components with anti-inflammatory properties have been studied: Curcumin Curcumin, the active compound in turmeric, has potent anti-inflammatory and antioxidant properties: Small studies suggest potential benefits for irritability and certain behaviors in ASD Well-studied for its general neuroprotective properties Poor bioavailability requires special formulations (e.g., combined with piperine or in liposomal form) Antioxidants Various antioxidant compounds may help address oxidative stress found in some individuals with ASD: Vitamin C and E : Work synergistically to combat oxidative damage Coenzyme Q10 : Supports mitochondrial function and provides antioxidant protection N-acetylcysteine (NAC) : Precursor to glutathione, the bodys master antioxidant Small clinical trials of NAC have shown promising results for irritability and repetitive behaviors in ASD, though larger studies are needed to confirm these effects

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J Affect Disord (2020) 276:81521