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As tires, brakes, and road surfaces wear down, they generate MPs that can settle on land or be carried into the air and water systems

When cytoplasmic catecholamine concentrations rise to levels that threaten to saturate both VMAT2 sequestration and mitochondrial monoamine oxidase (MAO) degradation pathways, the reversal of plasma membrane transporters provides a vital escape route (Underhill et al., 2021)

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