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DOI: 10.1165/rcmb.20120088OC 21
Studies have demonstrated that the lifespan of mice with OC is considerably reduced owing to the continuous activity of N1ICD, which leads to the aging of endothelial cells, increased expression of chemokines and the adhesion molecule VCAM1, and facilitates recruitment of neutrophils and invasion of tumors (70,74)
Clinical Assessment management Consider including in your assessments a recommendation to - - check B12 levels prior to the next injection, or every 3 months, to clarify status
Therefore, it would be useful to gain a global understanding of the differences in gene expression between the wild type and mutant strains
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