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In fact, their activity is greater on the abluminal membrane and they are voltage-sensitive

ClinNeurolNeurosurg 2009

10.1111/j.1464-5491.2005.01767.x

Der chemische Vorgang beginnt mit der Aktivierung langkettiger Fettsuren im Zytosol der Zelle, indem eine langkettige Fettsure mit Coenzym-A reagiert und so zu Acyl-CoA wird

These disruptions inhibit ATP synthesis and initiate apoptotic cascades, ultimately leading to neurodegeneration and immune dysregulation (Korotkov, 2023