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Banik S, Ghosh A

Mechanism of Action (How DSIP Works) CNS Penetration: Crosses the blood-brain barrier, exerting central effects on sleep regulation [Graf 1981]

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First, decreased expression of miR-128-3p in serum-derived exosomes from PCOS mouse models upregulates its target gene CSF1, which activates the p38/JNK signaling pathway and subsequently suppresses Nrf2-mediated transcriptional activity of SLC7A11